St Louis Cardinals 2025 Opening Day. Looking at the cardinals future payroll and prospect promotions, as well as future free agent classes and trade targets, here is my prediction for the opening day roster for st. Our 2025 regular season schedule is here!

Cardinals released their 2025 regular season schedule and opponents, including a visit from the minnesota twins on opening day of mlb’s championship season. The cardinals will open the season at home against the minnesota twins on thursday, march 27th.